Prof. Paul Laissue, MD, MSc, PhD, HDR
Molecular geneticist with more than 25 years of experience. He personally reviews every PLH Genetics case.
Background
- More than 100 indexed scientific publications (PubMed, Google Scholar, Scopus).
- He has worked with Universidad del Rosario (Bogotá), the Paris 5 and Paris 7 universities (now Université Paris Cité), Institut Pasteur and Institut Cochin in Paris, and the Haartman Institute at the University of Helsinki.
PLH Genetics was created so families can understand their genetic result in plain language and know what to ask their doctor.
Publications and profiles
Understanding Genetic Test Result Complexity
Genetic testing is often performed to better understand a medical condition. However, genetic concepts and test results can be difficult to understand by patients and their families.
In many cases, results clarify the origin and evolution of a condition and may support therapeutic decisions. However, even when appropriately indicated and technically well performed, reports may identify findings such as a Variant of Uncertain Significance (VUS) that do not clearly explain the clinical situation. Further high-level scientific reassessment can, in selected cases, provide additional clarity.
Our unique service therefore offers two levels of support.
First, we provide patients and families with a clear, easy-to-understand explanation of the genetic test performed, its purpose, and its results.
Second, when the report includes inconclusive findings such as a VUS, we provide a rigorous and independent scientific reanalysis that may contribute to a better clinical interpretation of the reported genetic findings.